Research Interests
Catalytic Asymmetric Synthesis, Development of new catalytic reactions of broad synthetic utility, Domino reactions, Green protocols in Organic Synthesis
BioSketch
Research
Selected Research Publications (Refereed Journals)
N. Singh, R. Budhwan, M. Rawat, R. K. Peddinti*
Catalyst-free facile synthesis of 2-(dihydropyridyl)benzothiazoles from (benzothiazol-2-yl)acrylonitriles: green route
Org. Biomol. Chem. 2026, 24, 3210–3217.
R. Budhwan, P. Dahiya, N. Singh, S. Chauhan, R. K. Peddinti*
Koser’s reagent-promoted synthesis of substituted isoxazoles and their photophysical properties
Org. Biomol. Chem. 2026, 24, 2742–2751.
M. S. Raza, K. Roshani, R. K. Peddinti*
Diastereodivergent access of spiro(pyrroloquinoline-pyrazolone) and oxa-azabicyclo[3.2.1]octane scaffolds via cascade approaches
Org. Chem. Front. 2026, 13, 1914–1926.
J. Sikarwar, J. Chauhan, R. K. Peddinti*
Highly diastereoselective synthesis of N,S-polyheterocyclic scaffolds via [3 + 2] cycloaddition of N-phenacylbenzothiazolium bromides
Eur. J. Org. Chem. 2026, 29, e202500986.
K. Roshani, M. S. Raza, R. K. Peddinti*
(4 + 2) ipso-Annulation of para-quinone methides with enone-tethered indoles: Access to spiro(pyrroloquinoline-cyclohexadienone) scaffolds
Adv. Synth. Catal. 2025, 367, e70105.
J. Chauhan, J. Sikarwar R. K. Peddinti*
PPh3-Promoted sulfa-Michael addition-driven cyclization: A divergent route to access spirothiochromanone derivatives
J. Org. Chem. 2025, 90, 15173–15184.
M. S. Raza, K. Roshani, R. K. Peddinti*
(4 + 3) Annulation of enone-tethered indoles with α-alkylidene succinimides: Access to seven-membered azepino[3,2,1-hi]indole scaffolds
Chem. Commun. 2025, 61, 12522–12525.
M. Rawat, R. Budhwan, P. Dahiya, A. Yadav, R. K. Peddinti*
Molecular iodine-catalyzed 1,6-conjugated addition of enaminones on para-quinone methides
Asian J. Org. Chem. 2025, 14, e00501 (doi.org/10.1002/ajoc.202500501).
M. Rawat, R. Budhwan, A. Yadav, R. K. Peddinti*
BF3·OEt2 Promoted 1,6-conjugate addition of para-quinone methides: A regioselective approach to diarylmethyl-substituted carbo- and heterocycles
Chem. Asian J. 2025, 17, e00595 (doi.org/10.1002/asia.202500595).
S. Renata,* N. Verma, R. K. Peddinti*
Surface-enhanced Raman spectroscopy as effective tool for detection of sialic acid as cancer biomarker
Spectrochim. Acta A Mol. Biomol. Spectrosc. 2025, 329, 125631
K. Roshani, M. S. Raza, R. K. Peddinti*
α-Alkylidene succinimides as ring-opening C2 synthons for base-promoted (4+2) annulation with 2‑hydroxyphenyl-substituted para-quinone methides: Synthesis of 2H-chromen-2-one and [2,3-c]pyrrole scaffolds
Org. Lett. 2024, 26, 9114–9119.
P. Dahiya, A. Yadav, R. Budhwan, M. Rawat, R. K. Peddinti*
Construction of arylthio/arylamino methylene bonds by addition-elimination of nitroolefins with aromatic thiols and amines
Org. Biomol. Chem. 2024, 22, 7664–7670.
A. Yadav, P. Dahiya, M. Rawat, R. K. Peddinti*
PTSA-Catalyzed [3 + 2] cycloaddition of in situ generated 3-ylidene oxindoles with coumarin-based N-phenyl enamine derivatives
Eur. J. Org. Chem. 2024, 27, e202301310.
P. Dahiya, A. Yadav, R. K. Peddinti*
Spirocyclization and Michael addition of 3-benzylidene succinimides: Route to spirocyclopentapyrrolidine-tetraones and benzylidene N-arylpyrrolidine-diones
Org. Biomol. Chem. 2023, 21, 9192.
P. Dahiya, A. Yadav, R. Budhwan, R. K. Peddinti*
Construction of polyheterocyclic compounds by Lewis-acid mediated intramolecular [3+2] cycloaddition reaction
Eur. J. Org. Chem. 2023, 26, e202300251.
R. Budhwan, M. Rawat, R. K. Peddinti*
Koser’s reagent mediated oxidation of aldoximes: Synthesis of isoxazolines by 1,3-dipolar cycloadditions
Synthesis, 2023, 55, 1904–1914.
S. Bisht, R. K. Peddinti*
Iodine-catalyzed reactions of aroylmethylidenes: Efficient access to α-substituted aryl ketones, functionalized naphthofurans and pyrroles
Asian J. Org. Chem. 2022, ajoc.202200576.
P. Dahiya, A. Yadav, M. Rawat, R. K. Peddinti*
[3 + 2] Cycloaddition reactions of 3-ylidene acenaphthylenones with 3-benzylidene succinimides and 1,4-benzoxazinone derivatives
Asian J. Org. Chem. 2022, ajoc.202200571.
D. Gairola, R. K. Peddinti*
Metal-free rapid sulfonylation of para-quinone methides and N-arylmaleimides with sulfonyl hydrazides via a free-radical pathway
Asian J. Org. Chem. 2022, ajoc.202200517.
D. Gairola, R. K. Peddinti
Methanesulfonic acid catalyzed Friedel-Crafts reaction of electron-rich arenes with N-arylmaleimides: A highly efficient metal-free route to access 3-arylsuccinimides
Synthesis 2021, 53, 1923-1930.
N. Dua, S. Ghosh, R. K. Peddinti
Zn(OTf)2-Catalyzed 1,6-conjugate addition of benzoxazinones to p-quinone methides: Access to 3,3-diaryl-2-(2-oxo-2H-1,4-benzoxazin-3-yl)propanoic acid esters
Synlett 2021, 32, 411-416.
B. Aegurla, N. Jarwal, R. K. Peddinti
Denitrative imino-diaza-Nazarov cyclization: Synthesis of pyrazoles
Org. Biomol. Chem. 2020, 18, 6100-6107.
P. Tehri, R. K. Peddinti
DBU-catalyzed [3 + 2] cycloaddition and Michael addition reactions of 3-benzylidene succinimides with 3-ylidene oxindoles and chalcones
Org. Biomol. Chem. 2019, 17, 3964-3970.
B. Aegurla, N. Jarwal, R. K. Peddinti
Dehydrative C- and S-alkylation: Access to highly substituted 1-sulfonylpropanes
Asian J. Org. Chem. 2019, 8, 555-563.
N. Sharma, R. K. Peddinti
Experimental and theoretical investigations of regioselective functionalization of 3-hydroxy bisindoles with thiols
Org. Biomol. Chem. 2018, 16, 9259-9268.
N. Taneja, R. K. Peddinti
Metal-free direct C-arylation of 1,3-dicarbonyl compounds and ethyl cyanoacetate: A platform to access diverse array of meta-functionalized phenols
Chem. Commun. 2018, 54, 11423-11426.
B. Aegurla, R. K. Peddinti
Metal-free sulfonylation of a,b-conjugated systems by using sulfonyl hydrazides
Asian J. Org. Chem. 2018, 7, 946-954.
U. K. Bhagat, R. K. Peddinti
Asymmetric organocatalytic approach to 2,4-disubstituted 1,2,3-triazoles by N2-selective aza-Michael addition
J. Org. Chem. 2018, 83, 793-804.
S. Bisht, R. Rani, R. K. Peddinti
Regioselective synthesis of bicyclic and polycyclic systems by cycloaddition reactions of alkenyl p-benzoquinones
J. Org. Chem. 2018, 83, 75-84.
A. Sharma, R. K. Peddinti
Direct asymmetric Mannich reaction catalyzed by D-glucosamine-derived organocatalysts
Synlett, 2018, 29, 630-634.
U. K. Bhagat, R. K. Peddinti
Regiospecific aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to chalcones: Synthesis of 2,4-disubstituted 1,2,3-triazoles under basic medium
Synlett, 2018, 29, 99-105.
S. Bisht, R. K. Peddinti
FeCl3-Mediated domino reaction of benzoxazinones with aroylmethylidene malonates: convenient synthesis to functionalized pyrrolobenzoxazines
J. Org. Chem. 2017, 82, 13617-13625.
B. Aegurla, R. K. Peddinti
The Diaza-Nazarov cyclization involving a 2,3-diaza-pentadienyl cation for the synthesis of polysubstituted pyrazoles
Org. Biomol. Chem. 2017, 15, 9643-9652.
N. Taneja, R. K. Peddinti
Catalyst-free sulfonylation of 2-methoxyphenols: Facile one-pot synthesis of (arylsulfonyl)catechols in aqueous media
Eur. J. Org. Chem. 2017, 5306-5314.
S. Sharma, S. K. R. Parumala, R. K. Peddinti
Lewis acid mediated site-selective synthesis of oxygenated biaryls from methoxyphenols and electron-rich arenes
J. Org. Chem. 2017, 82, 9367-9383.
N. Sharma, R. K. Peddinti
Iodine-catalyzed regioselective synthesis of multisubstituted pyrrole polyheterocycles free from rotamers and keto-enol tautomers
J. Org. Chem. 2017, 82, 9360-9366.
U. K. Bhagat, Kamaluddin, R. K. Peddinti
Base-mediated ring opening of meso-epoxides with 4-aryl-NH-1,2,3-triazoles: Synthesis of trans-2-(aryl-triazolyl)cycloalkanols
Synthesis 2017, 49, 3985-3997.
S. Sharma, P. Kumar, A. Sharma, R. K. Peddinti
BF3.OEt2-Mediated synthesis of 2-arylthio- and (N-aryl-2,5-dioxopyrrolidin-3-yl)-substituted 1,4-benzoxazine derivatives
Eur. J. Org. Chem. 2017, 3059-3071.
P. Singh, R. K. Peddinti
Waste-free swift-synthesis of symmetrical and unsymmetrical diarylmethyl thioethers from diaryl carbinols
Synlett 2017, 49, 3633-3642.
J. Agarwal, R. Rani, R. K. Peddinti
Mechanochemical grinding Diels-Alder reaction: Highly efficient and rapid access to bi-, tri- and tetracyclic systems
Synlett 2017, 28, 1336-1340.
A. Sharma, R. K. Peddinti
An efficient coupling of p-quinone mono imine ketals and aryl/alkyl thiols: Rapid synthesis of biaryl/aryl-alkyl sulfides
Eur. J. Org. Chem. 2017, 2230-2237.
A. Sharma, J. Agarwal, R. K. Peddinti
Direct access to the optically active VAChT inhibitor vesamicol and its analogues via the asymmetric aminolysis of meso-epoxides with secondary aliphatic amines
Org. Biomol. Chem. 2017, 15, 1913-1920.
N. Sharma, R. K. Peddinti
BF3.OEt2 Mediated regioselective reaction of electron-rich arenes with 3-ylidene oxindoles
J. Org. Chem. 2017, 80, 918-924.
S. Sharma, S. K. R. Parumala, R. K. Peddinti
Lewis acid mediated [3 + 2] coupling reaction of masked benzoquinones with styrenes: Facile synthesis of 2,3-dihydrobenzofurans
Synlett 2017, 28, 239-244.
S. Sharma, R. T. Naganaboina, R. K. Peddinti
Expedient synthesis of nitrovinyl substituted bicyclo[2.2.2]octenone scaffolds.
Rsc Adv. 2015, 5, 1000060-100069.
S. K. R. Parumala, R. K. Peddinti
Iodine catalyzed cross-dehydrogenative C-S coupling by C(sp2)-H bond activation: direct access to aryl sulfides from aryl thiols.
Green Chem. 2015, 17, 4068-4072.
(One of the top ten most accessed papers)
A. Sharma, J. Agarwal, N. B. Kamatham, R. K. Peddinti
Efficient and Catalyst-Free Michael Addition of d-Glucosamines to Acetylenic and Vinylic Compounds: Access to Vinylogous Carbamates of D-Glucosamine Derivatives.
Synlett. 2015, 26, 1398-1402.
S. K. R. Parumala, S. R. Surasani, R. K. Peddinti
S-Arylation of thiols with masked o-benzoquinones: Synthesis of alkyl aryl/diaryl sulfides.
New J. Chem. 2014, 38, 5268-5271.
S. R. Surasani, S. K. R. Parumala, R. K. Peddinti
Diels-Alder reactions of 4-halo masked o-benzoquinones. Experimental and theoretical investigations.
Org. Biomol. Chem. 2014, 12, 5656-5668.
R. T. Naganaboina, A. Nayak, R. K. Peddinti
Trifluoroacetic acid-promoted Michael addition-cyclization reactions of vinylogous carbamates.
Org. Biomol. Chem. 2014, 12, 3366-3370.
G. Choudary, R. T. Naganaboina, R. K. Peddinti
Expedient synthesis of novel 1,4-benzoxazine and butenolide derivatives.
RSC Adv. 2014, 4, 17969-17979.
R. T. Naganaboina, R. K. Peddinti
BF3.etherate mediated Friedel-Crafts alkylation of arenes with 2-hydroxy-1,4-benzoxazines: Synthesis of 2-aryl-1,4-benzoxazine derivatives.
J. Org. Chem. 2013, 78, 12819-12824.
S. K. R. Parumala, R. K. Peddinti
Reversal of polarity in masked o-benzoquinones: Rapid access to unsymmetrical oxygenated biaryls.
Org. Lett. 2013, 15, 3546-3549.
J. Agarwal, R. K. Peddinti
Synthesis and characterization of monosaccharide derivatives and application of sugar-based prolinamides in asymmetric synthesis.
Eur. J. Org. Chem. 2012, 6390-6406.
N. Bodipati, R. K. Peddinti
Hypervalent iodine mediated synthesis of carbamate protected p-quinone monoimine ketals and p-benzoquinone monoketals.
Org. Biomol. Chem. 2012, 10, 4549-4553.
N. Bodipati, R. K. Peddinti
Chemical generation of o-quinone monoimines: Rapid construction of novel 1,4-benzoxazine derivatives.
Org. Biomol. Chem. 2012, 10, 1958-1961.
(One of the top ten most accessed papers)
G. Choudhary, R. K. Peddinti
Introduction of a clean and promising protocol for the synthesis of Michael adducts and 1,4-benzoheterocycles: An emerging innovation.
Green Chem. 2011, 13, 3290-3299.
J. Agarwal, R. K. Peddinti
Glucosamine-based primary amines as novel organocatalysts for the asymmetric aldol reaction.
J. Org. Chem. 2011, 76, 3502-3505.
G. Choudhary, R. K. Peddinti
An expeditious, highly efficient, catalysed-free and solvent-free synthesis of nitroamines and nitrosulfides by Michael addition.
Green Chem. 2011, 13, 276-282.
J. Agarwal, R. K. Peddinti
Asymmetric Michael addition catalysed by sugar-based prolinamides in solvent-free conditions.
Tetrahedron Lett. 2011, 52, 117-121.
R. Rani, R. K. Peddinti
Michael reaction of ketones and b-nitrostyrenes catalyzed by camphor-10-sulfonamide-based prolinamide.
Tetrahedron Asymm. 2010, 21, 2487-2492.
J. Agarwal, R. K. Peddinti
Highly efficient and solvent-free direct aldol reaction catalyzed by glucosamine-derived prolinamide.
Tetrahedron Asymm. 2010, 21, 1906-1909.
R. Rani, R. K. Peddinti
Camphor-10-sulfonamide-based prolinamide organocatalyst for the direct intermolecular aldol reaction between ketones and aromatic aldehydes.
Tetrahedron Asymm. 2010, 21, 775-779.
J. Agarwal, A. Duley, R. Rani, R. K. Peddinti
Aminolysis of epoxides using iridium trichloride as an efficient catalyst.
Synthesis 2009, 21, 2790-2796.
Honors And Awards
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